Sustainable Health

Project HoneyBee

The honeybee is nature’s best collector and communicator of data. In this role, the honeybee provides the Center for Sustainable Health with an inspirational model for the collection and validation of data to sustain human health.

  • honeybee-logo-TM-rgbRecent advances in information technology and explosive growth in sophisticated but inexpensive data capture devices—biosensors—promise to revolutionize our ability to detect, diagnose, and prevent disease. By developing the ability to continuously record physiological parameters, we will pinpoint the transition from health to disease and intervene more effectively for improved health outcomes at a reduced cost. Importantly, our validation process is disease, device, and outcome-agnostic, particularly one that can handle the large variety of devices for clinical settings.

    We leverage our extensive experience in the careful validation of biomarkers for clinical application with a parallel methodology aimed at the utilization of physiological metrics obtained from wearable biosensors to address key clinical problems. To accomplish this goal, we enlist the considerable multidisciplinary resources of Arizona State University, while partnering with health systems such as the Mayo Clinic and Banner Healthcare in the United States and with Chang Gung University and Hospital system in Taiwan.
    We also see a pivotal role for the private sector, both for companies developing biosensor technologies and those companies seeking to improve employee health and their own fiscal health through low-cost but highly effective technologies. Lastly, technology innovation, population health and data management will be pivotal areas of focus for Project HoneyBee.
  • Identify an important clinical endpoint to predict

    Our nursing team will identify clinical situations where monitoring and predicting outpatient disease progression could improve patient outcomes and/or reduce healthcare costs. Our focus will be on the problem the sensor is intended to help solve, rather than only on the sensor itself.

    Identify relevant commercial wearable sensors

    Our interdisciplinary team of engineers, nurses, design and business students will investigate commercial wearable sensors to determine the physiological parameters they report and their accuracy and reliability, and compare performance for optimum cost/performance ratio.

    Establish cohort of patients

    We will then will analyze the data output of commercial devices to determine how to extract rich data parameters. Interdisciplinary teams will do small clinical trials to correlate—with high sensitivity and specificity–patient progression with data signals.

    Commercialization: Change the standard of care

    Finally, we will map a commercialization strategy.  Devices proven to improve patient outcomes while reducing healthcare costs would—along with its application—become appropriate subjects for randomized clinical trial and FDA approval.

  • Lee_Hartwell_Speaking_ForumASU’s new course “Interdisciplinary Approaches for Innovating in Healthcare Technologies” is designed to provide advanced undergraduate and Master’s level students in Engineering, Nursing and Business with an understanding of the evidentiary foundations of healthcare.

    Students will experience interprofessional education, with the goal of producing graduates who are able to work effectively with other professionals from different disciplines and with patients and families to deliver the highest quality of care and improve health outcomes.

    Students will learn to analyze the management of a disease from the standpoints of population impact, individual morbidity and mortality, risk factors, prevention strategies, early disease detection, therapeutic management and outcome metrics. We will consider the opportunities to develop new diagnostic tests for standard care in the developed world and to adapt existing technologies for use in poor countries. This course will also provide students with an understanding of the processes and protocols for biomedical device verification and validation testing for safe and efficacious medical diagnostics and devices. Students will also learn about managing the commercial development of a new device for successful introduction into the marketplace.

    This course is a hybrid course interweaving lecture, demonstration, laboratory work and student participation to cover the proposed materials.

    After devices have been tested, they will be deployed at our partner health systems with graduate-level students in an ongoing, IRB-approved 1000-patient cohort to monitor outpatients for disease progression or recovery for improved health outcomes and a reduced cost.

  • The HoneyBee Chronicles is a publication series that highlights unique perspectives from innovative leaders, pivotal work already underway, and ongoing needs and questions.

    Through interviews, personal reflections, and case studies—we illustrate the opportunities, advances in technology provide for improving health and lowering costs, as well as for transforming clinical practice and provider-interaction.


    July 31st, 2014

    Jamie Heywood - SquareAccuracy vs. Useful Feedback: Can Fitness Biosensors Revolutionize Prevention?

    The HoneyBee Chronicles Part Four

    An interview with Matt Buman, Assistant Professor in the School of Nutrition and Health Promotion, Arizona State University

    July 29th, 2014

    Jamie Heywood - SquareDigital Health: A Declaration of Independence from Antiquated Systems?

    The HoneyBee Chronicles Part Three

    An interview with Jamie Heywood, Chairman, PatientsLikeMe

    April 18th, 2014

    James-Levine2012 - SquareThe Infrastructure for Biosensors in Medicine:
    Better Mathematics and a Mindset Shift

    The HoneyBee Chronicles: Part Two

    An interview with James Levine, Professor of Medicine, Mayo Clinic, Arizona, Director,
    Obesity Solutions, Mayo Clinic and Arizona State University

    April 18th, 2014

    S LesterHealthcare Going Green: A Virtual Revolution
    The HoneyBee Chronicles: Part One

    An interview with Steven Lester, Consultant Cardiologist, Mayo Clinic, Arizona


    April 18th, 2014

    honeybee logoThe HoneyBee Chronicles
    The honeybee is nature’s best collector and communicator of data. Based
    on this framework, the Center for Sustainable Health has launched…

  • HoneyBeeCollaborativeCSHhomeWEB